Figure 1.
Flow diagram of the data selection.
This explains how the clinical trials for the analyses were selected.
Table 1.
Characteristics of the Studies Selected (N = 400).
Table 2.
Numbers of completed studies achieving Public Disclosure of Results (PDOR), publication and result posting to ClinicalTrials.gov (CTG) website, and time to do so (N = 400).
Table 3.
Factors predicting Public Disclosure of Results (PDOR) of completed studies (publication and/or posting to ClinicalTrials.gov (CTG) website).
Figure 2.
Cumulative rates of Public Disclosure of Results (PDOR) among selected studies categorized by funding source and phase of development (days from study completion to publication and/or posting to ClinicalTrials.gov website).
This X axis indicates days from study completion and Y axis indicates proportion of studies that achieved PDOR. - Green line shows phase 2 and industry studies. - Blue line shows phase 2 and non-industry/blended studies. - Red line shows phase 3/4 and industry studies. - Brown line shows phase 3/4 and non-industry/blended studies. * The median times to PDOR by each group is shown in Table S4 in Appendix S1.
Figure 3.
Effect of funding and study phase on proportion of studies that published their primary outcomes in a peer-review journal listed in PubMed by time since study completion.
This X axis indicates days from study completion and Y axis indicates proportion of studies that had publication in a peer-review journal. - Green line shows phase 2 and industry studies. - Blue line shows phase 2 and non-industry/blended studies. - Red line shows phase 3/4 and industry studies. - Brown line shows phase 3/4 and non-industry/blended studies. * The median times to publication by each group is shown in Table S5 in Appendix S1.
Figure 4.
Effect of funding and study phase on proportion of studies that made available their primary outcomes in ClinicalTrials.gov website by time since study completion.
This X axis indicates days from study completion and Y axis indicates proportion of studies that posted results to CTG. - Green line shows phase 2 and industry studies. - Blue line shows phase 2 and non-industry/blended studies. - Red line shows phase 3/4 and industry studies. - Brown line shows phase 3/4 and non-industry/blended studies. * Proportions of result posting to CTG by each group is shown in Table S6 in Appendix S1.