Table 1.
Demographics and neuroimaging features of neonates in the order of increasing seizure burden.
Figure 1.
Background EEG pattern in a neonate (case 9) with a right middle cerebral artery infarction.
Note the mild voltage reduction over the right hemisphere on EEG (blue channels) which is also evident on the aEEG with a wider band on the right in comparison to the left side. In addition, intermittent right-sided bursts of higher voltage sharpened theta activity are also evident. Some sleep cycling is also present over the left albeit disturbed but this is absent over the right side.
Figure 2.
Seizures arising from the left hemisphere corresponding with a left middle cerebral artery infarction on cranial MRI. B. Cranial MRI in a neonate (case 6). The sequence is an axial T2 turbo spin echo performed on day 7 of life. Note the characteristic focal spike and wave discharges over the left hemisphere with phase reversal over the left central region.
Table 2.
Characteristics of EEG and seizures.
Figure 3.
Characteristics of seizures and anticonvulsant administration in each neonate.
Vertical red lines denote the presence of electrographic-only seizures, vertical blue lines denote electroclinical seizures and vertical green lines denote obscured seizures. Horizontal black line denotes the period of EEG monitoring. Black crosses denote missing data. Timepoints bounded by black arrows denote the first-line anticonvulsant administration while the magenta arrows denote the second-line anticonvulsant administration.