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Figure 1.

Flowchart of patient numbers through the study.

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Table 1.

Medications taken by study patients.

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Table 2.

Mean changes in outcome measures.

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Figure 2.

Changes in plasma levels of MHPG in the manic state for BDI patients.

Each point represents the mean value. The significance of differences was calculated using repeated-measures ANOVA with post hoc Bonferroni testing (*p<0.05). Patients had significantly reduced plasma levels of MHPG throughout the manic syndrome, response and remission stages (repeated-measures ANOVA; F2,46 = 7.370, p = 0.002).

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