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Table 1.

IFOFq anterior segmentation results.

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Table 2.

IFOFq posterior segmentation results.

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Figure 1.

3D rendering of the left IFOFq.

The left IFOFq, reconstructed on the 20 subjects and normalized to the MNI space, is visualized from a lateral (A), anterior (B) and posterior (C) point of view. In A the path of the whole bundle can be appreciated, whereas B and C show its group average cortical terminations. Voxels that were visited in the residual bootstrap tractography in at least 20% of subject are shown.

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Figure 2.

IFOFq subdivision into portions connecting frontal regions to either the occipital (A) or the parietal lobes (B).

3D rendering of the left (blue) and right (yellow) IFOFocc reconstructed on the 20 subjects normalized to the MNI space (A). 3D rendering of the left (green) and right (red) portions of the IFOFq connecting frontal and parietal lobes reconstructed on the 20 subjects normalized to the MNI space (B). Voxels that were visited in the residual bootstrap tractography in at least 20% of subject are shown.

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Figure 3.

Schematic representation of the cortical regions connected by the IFOFq.

3D schematic representation in the MNI space of the Freesurfer-based regions, which showed connections through the IFOFq (left lateral view). Light green: superior frontal; yellow: caudal and rostral portions of middle frontal cortex; red: pars operularis, triangularis and orbitalis of the inferior frontal cortex; blue: lateral and medial portions of the orbitofrontal cortex; pink: superior parietal gyrus; green: angular gyrus; orange: occipital lobe; teal: fusiform gyrus. Fusiform gyrus was reached by IFOF termination only in its very caudal portion.

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Figure 4.

Axial representation of the IFOFq.

The left and right IFOFq were reconstructed on 20 subjects and normalized to the MNI space (radiological orientation). Colors represent the percentage of subjects (from 20% to 100%) in which a voxel was visited in the residual bootstrap tractography. The MNI coordinates of the selected axial slices are reported in the 3D rendering on the top.

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Figure 5.

Coronal representation of the IFOFq.

The left and right IFOFq were reconstructed on the 20 subjects and normalized to the MNI space (radiological orientation). Colors represent the percentage of subjects (from 20% to 100%) in which a voxel was visited in the residual bootstrap tractography. The MNI coordinates of the selected coronal slices are reported in the 3D rendering on the top.

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Figure 6.

Anterior terminations of the IFOFq.

Detailed description of the anterior terminations of the left IFOFq found in one illustrative subject. The colors of the subcomponent are consistent with the frontal VOIs color-code of Figure 3 and with Figure 13 by Sarubbo et al. Red: superficial layer; green: posterior terminations of the deep layer; yellow: middle terminations of the deep layer; blue: anterior terminations of the deep layer. a) anterior view; b) superior view; c) inferior view; d) lateral view; e) mesial view.

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