Table 1.
Initial characteristics of the study population (n = 1,272).
Figure 1.
Weight-loss progression during the 30-weeks of treatment stratified by emotional eating based on EEQ classification.
Weight-loss analyses within each single time point among the four classifications indicated significant differences exist (P = 0.03). Weight-loss progression differed significantly between the ‘very emotional eaters’ group and the three other groups (‘emotional eaters’, ‘low emotional eaters’, and ‘non-emotional eaters’) (P<0.05). The rate of weight-loss, as assessed by the slope of the weight-loss curves, also differed between the highly emotional group and the other groups (−0.002 vs. −0.003, P<0.05).
Table 2.
Treatment effectiveness in different categories of emotional eating.
Table 3.
Measures of obesity and dietary intake at baseline in emotional and non-emotional eaters.
Figure 2.
Differences in weight-loss between CLOCK genotypes and emotion eating classification as assessed by EEQ.
By dichotomizing the participants into ‘emotional eaters’ and ‘non-emotional eaters’, we found significantly different effects across genotypes at this locus (P for interaction = 0.017). Among minor C allele carriers, ‘emotional eaters’ lost significantly less weight than ‘non-emotional eaters’ (P = 0.0049). However, no significant differences were identified between ‘emotional eaters’ and ‘non-emotional eaters’ for total weight-loss among noncarriers (P = 0.454). Data are presented as mean ± s.e.m. We used (*) to indicate significant differences between emotional eating groups with the same genotype (P<0.050).