Table 1.
Definitions for the original and modified CTP classifications.
Table 2.
The distribution of HCC patients after modification of the CTP classifications.
Table 3.
Baseline demographics of all HCC patients and HCC patients with modified CTP class 0, A, B and C.
Figure 1.
Comparison of survival distributions between patients of different CTP classifications.
Patients with the new CTP class 0 were associated with a better long-term survival (panel B; p<0.001). Pairwise comparison between each CTP and modified CTP classes showed significant survival differences (panel A p<0.001).
Table 4.
Univariate and multivariate Cox regression survival analysis in HCC patients.
Table 5.
The proposed criteria for original and modified models of the BCLC staging system.
Table 6.
The proposed criteria for original and modified models of the CLIP and TIS staging systems.
Table 7.
Comparison of the prognostic ability among 4 BCLC-, 4 CLIP- and 4 TIS-based staging systems.
Figure 2.
Comparison of survival between stages in the original and modified models BCLC, CLIP and TIS with the lowest AIC score.
Patients with a more advanced stage were associated with a worse long-term survival in the original (panel A) and modified model B (panel B) BCLC systems, the original (panel C) and modified model A (panel D) CLIP systems, the original (panel E) and modified model A (panel F) TIS systems (all p<0.001). Pairwise comparison of survival differences between all stages in the modified BCLC, CLIP and TIS staging systems showed significant differences between each stage (all p<0.05), except for patients with modified BCLC stage 0 and A (p = 0.08).