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Table 1.

Demographic, clinical and neuropsychological assessment.

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Figure 1.

Cambridge Depersonalization Scale (CDS).

Subscales and Total Raw Scores. Higher scores in the first four subscales represent a higher presence of experiences from each of the DD main symptoms (all significant, except for Emotional Numbing). Frequency and duration refer to all DD symptoms. Total score is a product of the sum of the measures, and its established score cut off is 70. * expressed significant differences between DD patient and control sample.

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Figure 2.

Heartbeat Detection Task (HBD).

The Accuracy Index can vary between 0 and 1, with higher scores indicating better interoceptive sensitivity. * indicates significant differences between JM and the control sample.

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Figure 3.

Resting-state networks.

Most-often reported networks in previous research that contain groups of brain regions highly correlated with each other.

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Figure 4.

Networks connectivity matrices.

(A) Averaged correlation matrices for JM, control sample and conditions. Bottom rows shows t-values for test-t between JM and the control group. (B) T-value distributions for JM (red) and the IAC sample (blue).

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Figure 5.

Global Graph Theory Analysis.

Columns indicate each resting-state condition, and rows indicate each graph metric. The Y-axis shows raw metric scores, and the X-axis shows the range of thresholds, from 50 to 800, in steps of 50 (excluding extreme values where networks disaggregate). Boxes indicate significant and trend differences between JM and the control sample. Blue shadows represent controls' standard deviation area.

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Figure 6.

Local Graph Theory Analysis − Interoceptive macro-state.

Columns indicate each ROI from the interoceptive-emotional network, and rows indicate each graph metric. The Y-axis shows raw metric scores, and the X-axis shows the range of thresholds, from 50 to 800, in steps of 50 (excluding extreme values where networks disaggregate). Boxes indicate significant and trend differences between JM and the control sample. Blue shadows represent controls' standard deviation area.

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Figure 7.

Interpersonal Reactivity Index (IRI).

Subscales raw scores. * indicates significant differences between the DD patient and the control sample.

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Figure 8.

Empathy for pain task (EPT).

Neutral condition results: (A) categorization accuracy in percent; (B) reaction time in seconds of Harmful behavior and (C) average pain rating scores for each question after scenes of the neutral condition. Intentional condition results: (D) average empathy-related judgments scores for each question after scenes of this condition. * expressed significant differences between the DD patient and control sample.

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