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Figure 1.

Recruitment algorithm.

A total of 170 patients with CLD were consecutively enrolled. However 9 patients were excluded due to TE measurement failure (n = 3), unreliable LS measurement (n = 3), non-interpretable liver biopsies (n = 3), leaving 161 patients to be included in the statistical analysis. CLD, chronic liver disease; TE, transient elastography; LS, liver stiffness.

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Figure 1 Expand

Table 1.

Baseline characteristics (n = 161).

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Table 2.

Distribution of steatosis according to liver biopsy and CAP.

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Table 2 Expand

Table 3.

Comparison of patients with and without discordance.

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Table 3 Expand

Figure 2.

Percentage of patients with discordance according to histological steatosis grade and CAP value.

The percentages of discordance between liver biopsy and CAP were significantly higher in patients with steatosis grade 3 than in those with steatosis grade 0–2 (2 of 6 [33.3%] vs. 11 of 155 [7.1%], P = 0.021). Additionally, patients with CAP>323 dB/m had a higher percentage of discordance than those with CAP≤323 dB/m. (8 of 33 [23.1%] vs.5 of 128 [4.9%], P = 0.001). CAP, controlled attenuation parameter.

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Figure 2 Expand

Table 4.

Independent predictors of discordance between liver biopsy and CAP.

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Table 4 Expand