Figure 1.
Pedigree and genetic analyses of the two large families.
Genetic analyses were performed on all individuals indicated by filled, divided and open symbols. Pedigree symbols: slashed symbol, deceased individual; open symbol, unaffected individual; divided gray symbol, carrier for M769H-fs mutation; divided black symbol, carrier for H1069Q mutation; filled symbol, affected individual with compound heterozygous genotype. A filled arrowhead indicates proband. Roman numbers indicate generations.
Table 1.
Clinical and laboratory findings of WD patients.
Table 2.
The SNPs of the ATP7B gene in healthy control group.
Table 3.
Genotype-phenotype correlations found in patients with Wilson’s disease.