Table 1.
Age, body weight, radiographic and clinical features of the selected cats.
Figure 1.
Photograph of the placement of the von Frey probe.
During evaluation, the cats stood in a meshed cage, the probe tip was placed perpendicular to the plantar surface of the foot, and an increasing force was applied without manipulating the limb.
Figure 2.
Photograph of the mechanical repetitive stimuli quantitative sensory testing experimental setting.
Cats were placed in a meshed cage. The mechanical stimulator, which was embedded in a small band, was placed around the distal aspect of the cat's foreleg (left in this photograph) and connected to the stimulator device, while a dummy band was installed on the contralateral leg (right in this photograph).
Table 2.
Characterization of the mechanical stimuli provided by each stimulation profile.
Table 3.
Details of the mixed model analyses.
Figure 3.
Characterization of osteoarthritis (OA) using chronic pain evaluation methods: A- Least squares means and 95% confidence interval of the log-transformed most affected limb peak vertical ground reaction force (PVF) after-exercise by OA status.
B- Least squares means and 95% confidence interval of the motor activity (MA) intensity by OA status. C- Least squares means and 95% confidence interval of the log-transformed von Frey anesthesiometer-induced paw withdrawal threshold by OA status.
Figure 4.
Number of stimuli reached and 95% confidence interval (inverse link of the least squares means estimates and 95% confidence interval obtained using the Poisson generalized linear modelling) following repetitive mechanical stimuli: A- by stimulation profiles (#1 to 4); B- by stimulation profiles and osteoarthritis (OA) status.
Adj-P = adjusted p-value.