Figure 1.
Graphical user interface of the BraTumIA software.
Data can be loaded from the buttons at the top, the left side offers different options for processing and visualization and the largest part of the screen depicts the different MRI modalities with optional overlay of the segmentation results.
Figure 2.
Comparison of the difference in 2- dimensional measurements of two expert raters and the diameters extracted from the automatic segmentations on the study population of 25 patients.
SPD = sum of products of diameters in mm2. Wide horizontal bars indicate the mean and the shorter horizontal bars indicate the SD.
Figure 3.
Box and whisker plots (min -max) of TV+, TV and CETV between manual raters (inter-rater (IR)), automatic segmentation versus expert rater 1 (AE 1); and automatic segmentation versus expert rater 2 (AE 2) for A: Dice coefficients B: PPV = Positive predictive values C: Sensitivity for the sub-compartment segmentations.
Figure 4.
Scatter plot of the absolute volume measurement for TV+, TV and CETV (from left to right).
Volumes measured automatically are shown on the x-axis, volumes measured manually by the two expert raters are shown on the y-axis.
Table 1.
Statistics of Dice coefficients from the MICCAI BraTS 2012 testing dataset compared to the Dice coefficients on our clinical study dataset (CS).
Table 2.
Spearman's rank correlation coefficients (ρ) of TV+, TV and CETV.
Figure 5.
The figures show the original images and the segmentations as overlays on the post-contrast T1-weighted images for a patient with a good overlap of manual and automatic segmentation.
Upper row: an axial slice of the original images (T1w, T1wGd, T2, FLAIR from left to right). Bottom row left column: manual segmentation, right column: automatic segmentation. Color code for segmentations: red = necrosis, yellow = enhancing tumor, blue = non-enhancing tumor, green = edema. TV+ corresponds to a combination of all colors, TV corresponds to red+yellow+blue compartments, CETV corresponds to the yellow compartment.
Figure 6.
The figures show the original images and the segmentations as overlays on the post-contrast T1-weighted images for a patient with a moderate overlap of manual and automatic segmentation (CETV does not match well).
Upper row: an axial slice of the original images (T1w, T1wGd, T2w, FLAIR from left to right). Bottom row left column: manual segmentation, right column: automatic segmentation. Color code for segmentations: red = necrosis, yellow = enhancing tumor, blue = non-enhancing tumor, green = edema. TV+ corresponds to a combination of all colors, TV corresponds to red+yellow+blue compartments, CETV corresponds to the yellow compartment.
Table 3.
Regional Differences in Dice overlap according to localization.