Table 1.
Accuracy and response time by conditions in the emotional faces task.
Figure 1.
Amygdala and visual cortex BOLD activation to stimulus novelty.
BOLD fMRI responses in the amygdala and visual cortex obtained for the contrast ”1st presentation” >”2nd presentation”. (A) Statistical parametric maps (SPM) demonstrating the responses in visual cortex for the given contrast. The image is thresholded at p = 0.005, k = 25 voxels for illustrative reasons. The colors refer to t-values as coded in the bar to the left of the image (B) Statistical parametric maps (SPM) demonstrating the responses in amygdala for the same contrast. The image is thresholded at p = 0.005, k = 25 voxels for illustrative reasons. (C) Beta values for the peak voxel in right amygdala (x = 24, y = −6, z = −14) and right inferior occipital gyrus (x = 34, y = −78, z = −12) for the conditions 1st presentation and 2nd presentation of the emotional faces.
Figure 2.
Correlation between state anxiety scores and individual amygdala activation.
Negative correlation between the individual state anxiety scores and the activity in right amygdala. Subjects with a high score on state anxiety had less amygdala signal change between the 1st time and the 2nd time presentation of the emotional faces. (A) Statistical parametric map (SPM) showing the right amygdala cluster. The image is thresholded at p<0.005, 25 voxels extent threshold, for illustrative reasons. The colors refer to t-values as coded in the bar to the right of the image (B) Scatter-plot demonstrating the negative correlation.
Table 2.
BOLD fMRI responses in amygdala and visual cortex for the contrast “1st presentation” > “2nd presentation”.
Figure 3.
BOLD activation by condition in right inferior occipital gyrus.
Beta values for the peak voxel in right inferior occipital gyrus (x = 34, y = −78, z = −12) for the conditions 1st presentation, 2nd presentation and other presentations of the emotional faces. The figure illustrates that the right inferior occipital gyrus BOLD fMRI response was significantly reduced in the 2nd compared to the 1st presentation. However, the BOLD response during the 2nd presentation was significantly greater than the mean response from the remaining presentations of the faces.
Figure 4.
Psychophysiological interaction analysis.
The results of the psychophysiological interaction analysis. (A) Statistical parametric map (SPM) showing regions in the visual cortex that showed condition-specific BOLD signal changes with right amygdala activity. The image is thresholded at p<0.005, 25 voxels extent threshold, for illustrative reasons. The colors refer to t-values as coded in the bar to the right of the image (B) Scatter plot with regression lines demonstrating the pattern of functional connectivity. The x-axis represents activity in the right amygdala (beta values) peak voxel and the y-axis represents activity in the right inferior occipital gyrus peak voxel (beta values).