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Figure 1.

Principle diagram of a confocal laser Raman spectrophotometer.

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Table 1.

Tentative assignments of Raman bands (human tissue).

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Figure 2.

The Raman spectrum of gastric mucosal tissue DNA (Normal tissue: N. Gastric cancer tissue: C. Elution buffer: TE).

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Figure 3.

The Raman spectrum of gastric mucosal tissue DNA (Normal tissue: N Gastric cancer tissue: C).

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Figure 4.

Normal mucosal tissue (H&E 200x).

4-2 Confocal Raman microscopy image of a normal mucosal tissue section.

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Figure 5.

Gastric cancer tissue (H&E 200x).

Figure 5-2 Confocal Raman microscopy image of a gastric cancer tissue section.

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Figure 6.

Raman spectra of nuclei from mucosal sections (Normal: n. Cancer: c. H&E dyes: d).

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Table 2.

The distribution of signature peaks in the Raman spectra of nuclei from H&E-stained sections.

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Figure 7.

Raman spectra of 15 gastric cancer tissues.

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Figure 8.

Raman spectra of 15 normal mucosal tissues.

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Figure 9.

Average Raman spectra of mucosal tissues (Normal: n. Gastric cancer: c).

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Figure 10.

Image of tissue obtained by confocal Raman spectrometry (100x).

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Figure 11.

Distribution of signature peaks of gastric cancer and normal tissue.

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Table 3.

Distribution of Raman peaks of tissues.

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Figure 12.

ROC curve from the ratio of relative peak intensity (Two Independent Sample t-Test).

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Table 4.

Ratio of relative peak intensity (Two Independent Sample t-Test).

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