Table 1.
Time domain indexes derived from HP and QT series in the NMC-MC protocol.
Table 2.
Time domain indexes derived from HP and QT series in the DAY-NIGHT protocol.
Table 3.
Time domain indexes derived from HP and QT series in the BBoff-BBon protocol.
Figure 1.
Comparison between RMSE indexes derived from HP and QT series.
RMSE mean (plus standard deviation) assessed at short time scale (i.e. τ = 1), RMSEτ = 1 (a,d,g), at medium time scales (i.e. τ = 2–4), RMSEτ = 2–4 (b,e,h), and at long time scales (i.e. τ = 5–12), RMSEτ = 5–12, (c,f,i) is shown as a function of the time series (i.e. HP and QT). RMSEτ = 1, RMSEτ = 2–4, and RMSEτ = 5–12 were obtained by pooling RMSE values computed BBoff during DAY (a,b,c), BBoff during NIGHT in (d,e,f), and BBon during DAY (g,h,i), The symbols § and ° indicate a significant difference with p<0.001 and p<0.05 respectively.
Figure 2.
RMSE at short time scale over HP and QT series.
RMSE mean (plus standard deviation) assessed at short time scale (i.e. τ = 1) over HP series, RMSEHP,τ = 1 (a,c,e), and QT series, RMSEQT,τ = 1 (b,d,f), is shown as a function of the experimental protocol. RMSEHP,τ = 1 and RMSEQT,τ = 1 are depicted as a function of the group of subjects in the NMC-MC protocol in (a) and (b) respectively, as a function of the period of analysis in the DAY-NIGHT protocol in (c) and (d) respectively, and as a function of the therapy in the BBoff-BBon protocol in (e) and (f) respectively. The gray, dark and white bars are relevant to NMC, ASYMP and SYMP individuals, respectively. The symbols * indicates a significant difference between experimental conditions (i.e. DAY versus NIGHT, BBoff versus BBon) within the same group with p<0.05.
Figure 3.
RMSE at medium time scales over HP and QT series.
RMSE mean (plus standard deviation) assessed at medium time scales (i.e. τ = 2–4) over HP series, RMSEHP,τ = 2–4 (a,c,e), and QT series, RMSEQT,τ = 2–4 (b,d,f), is shown as a function of the experimental protocol. RMSEHP,τ = 2–4 and RMSEQT,τ = 2–4 are depicted as a function of the group of subjects in the NMC-MC protocol in (a) and (b) respectively, as a function of the period of analysis in the DAY-NIGHT protocol in (c) and (d) respectively, and as a function of the therapy in the BBoff-BBon protocol in (e) and (f) respectively. The gray, dark and white bars are relevant to NMC, ASYMP and SYMP individuals, respectively. The symbol * indicates a significant difference between experimental conditions (i.e. DAY versus NIGHT, BBoff versus BBon) within the same group with p<0.05. The symbol # indicates a significant difference between groups within the same experimental conditions (i.e. DAY, NIGHT, BBoff or BBon) with p<0.05.
Figure 4.
RMSE at long time scales over HP and QT series.
RMSE mean (plus standard deviation) assessed at long time scales (i.e. τ = 5–12) over HP series, RMSEHP,τ = 5–12 (a,c,e), and QT series, RMSEQT,τ = 5–12 (b,d,f), is shown as a function of the experimental protocol. RMSEHP,τ = 5–12 and RMSEQT,τ = 5–12 are depicted as a function of the group of subjects in the NMC-MC protocol in (a) and (b) respectively, as a function of the period of analysis in the DAY-NIGHT protocol in (c) and (d) respectively, and as a function of the therapy in the BBoff-BBon protocol in (e) and (f) respectively. The gray, dark and white bars are relevant to NMC, ASYMP and SYMP individuals, respectively. The symbol * indicates a significant difference between experimental conditions (i.e. DAY versus NIGHT, BBoff versus BBon) within the same group with p<0.05. The symbol # indicates a significant difference between groups within the same experimental conditions (i.e. DAY, NIGHT, BBoff or BBon) with p<0.05.