Figure 1.
Probability density functions of nodal and distant metastases from the time of tumor onset, using the estimated parameters ξ = 0.01,
= 8.05×10−9,
= 2.78×10−9, K = 3.80 and
= 1.15.
Table 1.
The estimates of model parameters, with asymptotic confidence intervals.
Figure 2.
Comparison of the model fit in the period of 1995–1999 to the data of SEER 2004–2008.
(a) the stage distribution conditional on tumor size and (b) the tumor size distribution; (c) Comparison of the predictive model 1988–1999 and SEER 1988–1999, where the data is summarized as stage distribution conditional on tumor size.
Table 2.
Comparison of the lung cancer patient population predicted by our model (1988 to 1999) with data from the SEER database (from 1988 to 1999 and from 2004 to 2008).
Figure 3.
Tumor size distribution in predictive models, (a) Stage N0,M0 in SEER (2004–2008) and model (1988–1999), stage Localized by SEER standard in SEER (1988–1999), (b) Stage Nx,M0 (x≥1) in SEER (2004–2008) and model (1988–1999), stage Regional by SEER standard in SEER (1988–1999), (c) Stage M1 in SEER (2004–2008) and model (1988–1999), stage Distant by SEER standard in SEER (1988–1999).
Table 3.
Variables not directly observable for the detected tumors in the predicted lung cancer population (1988–1999).