Figure 1.
Light blue crest (LBC) appears as blue-whit lines visible on the epithelial surface under narrow band imaging with magnification endoscopy (NBI-ME) (original photo, Olympus GIF-H260Z, under 80×magnification).
Table 1.
Original Table of Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool [9].
Figure 2.
Study selection flow diagram.
Table 2.
Characteristics of studies included in meta-analysis of accuracy of light blue crest signto diagnose gastric intestinal metaplasia.
Table 3.
Application of the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool to the five studies included in the meta-analysis.
Figure 3.
Results of per-lesion analysis of four studies.
Per-lesion analysis of diagnostic performance of the light blue crest (LBC) sign under narrow band imaging with magnification endoscopy (NBI-ME) to diagnose gastric intestinal metaplasia(IM): (a) pooled sensitivity; (b) pooled specificity; (c) pooled positive likelihood ratio; (d) pooled negtive likelihood ratio; (e) symmetric receiver operator curve characteristic (SROC) curve and area under curve(AUC).
Figure 4.
Results of per-lesion analysis of three studies.
Per-lesion analysis of diagnostic performance of the light blue crest (LBC) sign under narrow band imaging with magnification endoscopy (NBI-ME) to diagnose gastric intestinal metaplasia(IM): (a) pooled sensitivity; (b) pooled specificity; (c) pooled positive likelihood ratio; (d) pooled negtive likelihood ratio; (e) symmetric receiver operator curve characteristic (SROC) curve and area under curve(AUC).