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Table 1.

Specificity of the test: Absence of interference by fibrin degradation products.

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Figure 1.

Evolution of SF and D-dimer levels in patients under anticoagulant therapy.

SF and D-dimer (D-Di) concentrations were determined daily in patients before and after starting anticoagulant therapy.

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Figure 1 Expand

Figure 2.

ROC curves for DVT and PE.

ROC Curves established for Pulmonary Embolism and for Deep Vein Thrombosis Open squares : Sensitivity Closed square : Specificity.

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Table 2.

Roc appendices for pulmonary embolism and for deep vein thrombosis.

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Table 2 Expand

Table 3.

Plasma Soluble Fibrin (SF) and D-dimer levels in Patients with suspected Pulmonary Embolism (PE) or Deep Vein Thrombosis (DVT).

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Figure 3.

Distribution of the levels of SF and D-dimer in patients with suspected pulmonary embolism (PE) or deep vein thrombosis.

Evaluation of median and 25th and 75th percentiles. (A) Soluble fibrin concentration. (B) D-dimer concentration. •/Closed circles: patients with PE or DVT; ○/open circles, patients without PE or DVT. The bars depict the median with interquartile ranges. The double broken bars represent the upper normal value.

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Figure 3 Expand

Table 4.

Evaluation of the area under the ROC (Receiving Operating Characteristic) curve for SF and D-dimer derived from patients with suspected Pulmonary Embolism or Deep Vein Thrombosis.

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Table 5.

Sensitivity, Specificity, Positive- (PPV) and Negative-Predictive Values (NPV) (95% Confidence Intervals) for Soluble Fibrin (SF) and D-dimer concentrations in Pulmonary Embolism and Deep Vein Thrombosis.

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