Table 1.
Patient Demographics.
Table 2.
Association of clinical stages of lung cancer with ThinPrep.
Figure 1.
Cytomorphology of lung squamous cell carcinoma (SCC) using ThinPrep bronchial brushing cytology.
Small clusters of malignant cells with features of poorly differentiated carcinoma. (A), Well-differentiated SCC. Cytological features are characterized by individual cells or cohesive sheets of tumor cells with clear cell borders and a dense cytoplasm. (B), Poorly differentiated SCC. Cytology shows high cellularity and small groups of tumor cells. The nuclear/cytoplasmic (N/C) ratio was usually high (Papanicolaou staining; the original magnification was 400×).
Figure 2.
Cytomorphology of lung adenocarcinoma (ADC) in ThinPrep bronchial brushing cytology.
(A and B), Typical features of ADC in cytology include cellular clusters with a deep focus due to the three-dimensional clusters of large vacuolated cells. Sometimes, the individual cells or acinar (glandular) arrangements were visible in the cytology slides. The nuclear/cytoplasmic (N/C) ratio was usually high (Papanicolaou staining; the original magnification was 400×).
Figure 3.
Cytomorphology of small cell lung carcinoma (SCLC) in ThinPrep bronchial brushing cytology.
(A and B), The features of SCLC in cytology included a biphasic population of viable and degenerating tumor cells. These cells had a scant cytoplasm with a thin cyanophilic rim, single or loose clusters, molding, and DNA artifacts. The nuclear/cytoplasmic (N/C) ratio was usually high (Papanicolaou staining; the original magnification was 400×).
Table 3.
Association of ThinPrep Bronchial Brushing Cytology with Lung Cancer Histology.