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Figure 1.

Flow diagram the systematic review literature search results.

A total of 91 systematic reviews of intervention animal studies were included.

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Figure 1 Expand

Figure 2.

Number (n) of published SRs of intervention animal studies per publication year (2005–2012).

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Figure 2 Expand

Figure 3.

Percentages of SRs per number of internal validity item scored.

Zero items by 47.3%, one item all randomisation, two items randomisation and one level of blinding, three items randomisation, blinding of caretaker/investigator and blinding of outcome assessment or randomisation, one level of blinding and drop-outs) and all four items by 3.3%.

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Figure 3 Expand

Figure 4.

Percentage of primary animal studies assessed per validity item; yes or no.

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Figure 4 Expand