Figure 1.
Blood collection schedule and analysis plan.
Table 1.
Baseline patient characteristics.
Table 2.
Correlation between blood biomarker levels and stable (baseline) lung function.
Table 3.
Coefficient of variation for blood biomarker levels over 3 consecutive stable visits.
Figure 2.
Boxplot of sCD14 levels in patients who did vs. did not experience a pulmonary exacerbation within 4 months.
Table 4.
Comparison of blood biomarker levels in patients who did vs. did not experience a pulmonary exacerbation requiring IV antibiotics within 4 months of a stable blood collection.
Figure 3.
Defining an optimal sCD14 threshold value to predict pulmonary exacerbations requiring IV antibiotics within 4 months.
Table 5.
Comparison of paired stable-exacerbation biomarker levels.
Figure 4.
Paired stable-exacerbation biomarker levels for biomarkers with statistically significant (<0.05) or borderline significant change (p<0.10).