Table 1.
Overview of samples.
Table 2.
First trimester screening test parameters for the high, intermediate and low risk pregnancies for cases meeting quality control criteria for chromosome Y assessment (N = 195).
Figure 1.
Fetal DNA fractions among pregnancy risk groups.
Horizontal line shows the overall median fetal DNA fraction.
Figure 2.
Frequency distributions of the range of fetal DNA fractions found in male euploid pregnancies.
Fetal DNA fractions are compared among pregnancies at high or low risk for trisomy 21.
Figure 3.
Relationships between fetal DNA fractions with the first trimester screening parameters between pregnancy risk groups.
Depicted are pregnancies at high risk (purple circles), intermediate risk (green diamonds) and low risk (blue triangles).
Figure 4.
Relationship of the z score with fetal DNA fractions in maternal plasma.
Solid line marks the z score cutoff of 3 for detecting elevated proportions of chromosome 21. Dash line shows the correlation between the z score and fetal DNA fractions for the trisomy 21 cases.