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Figure 1.

Process flow diagram for identification and antimicrobial susceptibility testing of bacteria directly from positive blood culture bottles using the Lysis-Filtration Method with MALDI-TOF VITEK Mass Spectrometry and the VITEK®2 System.

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Table 1.

Susceptibility testing of bacteria from positive blood culture bottles by using a Lysis-Filtration Method, MALDI-TOF Mass Spectrum Analysis with SARAMIS Database, and the VITEK®2 System.

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Table 1 Expand

Table 2.

Microorganism-antimicrobial combinations that did not result in agreement with conventional methodsa.

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Table 2 Expand

Figure 2.

Average time in hours to results of ID or AST from (a) time when blood culture bottle was flagged as positive or (b) time when blood was collected from patient.

For the Lysis-Filtration Method, ID was performed using VITEK MS, AST was performed using VITEK®2. AST = antimicrobial susceptibility testing. GN = Gram-negative organisms; GP = Gram-positive organisms; ID = identification; VITEK MS = MALDI-TOF VITEK MS RUO.

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Figure 2 Expand

Table 3.

Comparison of time to ID and AST between Lysis-Filtration method and conventional methods (hours)a.

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Table 3 Expand