Figure 1.
Inbred strain differences in pre-training performance, and in discrimination and reversal learning.
(A) Sessions to autoshaping, touch and punish criterion. (B) Sessions to discrimination and reversal criterion. Errors (C) and correction errors (D) to discrimination criterion. AP<.05 autoshaping session relative to C57BL/6J, TP<.05 touch sessions relative to C57BL/6J, pP<.05 punish session relative to C57BL/6J, *P<.05 discrimination, reversal, errors or correction errors relative to C57BL/6J. n = 9–27 per strain. Data are Means ± SEM.
Figure 2.
Inbred strain differences in reversal learning.
Errors (A) and correction errors (B) to reversal criterion. Errors (C) and correction errors (D) made during early reversal. Errors (E) and correction errors (F) made during late reversal. *P<0.5 relative to C57BL/6J. n = 2–27 per strain. Data are Means ± SEM.
Figure 3.
Stress effects on reversal learning in DBA/2J and C57BL/6J mice.
(A) Sessions to reversal learning criterion. Errors (B) and correction errors (C) to reversal criterion. Sessions to early and late stage reversal (D). Errors (E) and correction errors (F) made during early and late stage reversal. *P<.05 stressed vs. non-stressed control C57BL/6J, †P<.05 non-stressed DBA/2J vs. non-stressed C57BL/6J, ‡P<.05 stressed DBA/2J vs. stressed C57BL/6J. n = 10–13 per stress group, per strain. Data are Means ±SEM.
Figure 4.
BXD-RI strain differences in training performance, and in discrimination and reversal learning.
(A) Sessions to autoshaping, touch and punish criterion. (B) Sessions to discrimination, reversal and extinction criterion. Errors (C) and correction errors (D) to discrimination criterion. n = 1–16 per strain. Data are Means ± SEM.
Figure 5.
BXD-RI strain differences in reversal learning.
Errors (A) and correction errors (B) to reversal criterion. Errors (C) and correction errors (D) made during early reversal. Errors (E) and correction errors (F) made during late reversal. n = 1–14 per strain. Data are Means ± SEM.
Table 1.
Genetic correlations between measures of touchscreen performance and learning.
Table 2.
Principal components analysis of touchscreen performance and learning.