Table 1.
APOC1 (rs11568822) polymorphism and AD.
Figure 1.
Flow diagram of study selection.
A total of 15 articles, 14 published articles plus our study, were included in the meta-analysis. Of them, two published articles were regarded as two different studies as they included different subpopulations.
Table 2.
Main characteristics of included studies in meta-analysis.
Figure 2.
Forest plot for the association between the APOC1 rs11568822 polymorphism and AD risk using recessive model (fix effects model).
Table 3.
Summary of meta-analysis results in different models.
Table 4.
Summary of stratified analysis results in APOE ε4 non-carriers.
Table 5.
Analysis of accumulation effect of APOC1 and APOE.
Figure 3.
Funnel plots of APOC1 rs11568822 polymorphism in dominant model and heterozygote comparison model.
The shapes of the funnel plots revealed a degree of asymmetry visually which indicated publication bias may exist. OR: odds ratio; Log [OR]: natural logarithm of OR; SE: standard error; SE (Log [OR]): standard error of Log [OR]. Each point represents a separate study for the indicated association. (A) Dominant model. (B) Heterozygote comparison model.