Table 1.
Demographics, clinical characteristics of the Chinese renal transplant recipients.
Table 2.
Frequencies of allelic variants in the Chinese renal transplant recipients.
Figure 1.
Box-and-whisker plot of tacrolimus C0/D for different genotypic groups.
The boxes represent the median, 25th and 75th percentiles of the data. The circles represent deviant cases. The X-axis gives the times (days 1–3, 6–8 and 12–14, and the period of stable conditions after transplantation). The Y-axis gives the C0/D. Genetic variants are: A, CYP3A5*3; B, CYP3A4*1G; and C, CYP3A4 rs4646437 T>C. The p values among the genetic groups are given above the box-and-whisker plot.
Table 3.
Comparison of the tacrolimus C0/D in the different groups classified by genetic variant genotypes.
Table 4.
Comparison of the tacrolimus C0/D in the different genotypic groups on the time achieving target blood tacrolimus concentrations.
Table 5.
The impact of the genetic variants on the time to achieve the target blood tacrolimus concentrations.
Table 6.
Tacrolimus C0/D in CYP3A4*1/*1G genotypes classified by different CYP3A5 expressers.
Table 7.
Tacrolimus C0/D in CYP3A4 rs4646437 genotypes classified by different CYP3A5 expressers.