Table 1.
Categorization of the Study Population.
Table 2.
Demographic and characteristics of the study population.
Table 3.
Single and combined diagnostic parameters of T-SPOT.TB on SEMC and PBMC.
Figure 1.
Frequencies of MTB-specific IFN-γ secreting T cells in serous effusion and peripheral blood.
The frequencies of ESAT-6 and CFP-10 specific IFN-γ secreting T cells in SEMC were significantly higher than those in PBMC (P = 0.002 for ESAT-6, P = 0.012 for CFP-10). The counts of IFN-γ secreting T cells specific for CFP-10 appeared higher than ESAT-6, but the difference were not statistically significant (P = 0.573 for serous effusion, P = 0.092 for peripheral blood). PBMC: peripheral blood mononuclear cell; SEMC: serous effusion mononuclear cells
Figure 2.
ROC curves for T-SPOT.TB on SEMC and PBMC in patients with suspected tuberculous serositis.
The AUC of ROC curve was 0.938 (95%CI: 0.900–0.975,P<0.001) for T-SPOT.TB on SEMC, which was higher than that of T-SPOT.TB on PBMC (0.811,95%CI: 0.742–0.880,P<0.001). PBMC: peripheral blood mononuclear cell; SEMC: serous effusion mononuclear cells; ROC: receiver operating characteristic; AUC: area under the receiver operating characteristic curve.