Table 1.
Characteristics of the study population.
Table 2.
Expression levels of obesity marker genes.
Figure 1.
Serum concentrations and gene expression levels of obesity markers in relation to gender and diabetes.
Data represent mean (±SE) of the serum concentrations of leptin and adiponectin (A) and gene expression of leptin, adiponectin, TNFα and PPARγ normalised to the gene expression of TBP gene*1000 of AT samples (B, C, D, E). Significant differences between men (n = 17) and women (n = 33) (B, C), diabetic (n = 8) and non diabetic patients (n = 42) (D, E) are indicated with asterisks (Mann Whitney U-test; *p≤0.05; **p≤0.01).
Table 3.
Spearman correlation coefficients (ρ) of total CT, VAT/SAT ratio and BMI with obesity marker expression levels in fat tissue (gene expression values) and serum (adipokine concentrations) in the overall population (n = 50).
Table 4.
Spearman correlation coefficients (ρ) of total CT, VAT/SAT ratio and BMI with obesity marker expression levels in fat tissue (gene expression values) and serum (adipokine concentrations) related to gender and diabetic status.
Figure 2.
Correlations between obesity marker genes and POP concentrations in AT.
Scatterplots are representing gene expression values of obesity maker genes (X-axis) in relation to the POP concentrations (Y-axis). Only highly significant spearman correlations (p≤0.007) are shown, ρ-values and p-values of the Spearman correlations are indicated on the scatterplot.
Table 5.
Spearman correlations coefficients of POP levels in AT with serum concentrations (leptin and adiponectin) and gene expression in fat tissue.
Table 6.
Overview of standard linear regression analyses with obesity marker levels as dependent variables and POP levels in VAT/SAT, BMI and gender or diabetes as independent variables.
Figure 3.
Overview of the major findings of this manuscript.
A. Levels of obesity markers in VAT, SAT and serum of the obese population depending on gender and diabetic status. B. Associations between obesity markers and POP levels.