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Figure 1.

PRISMA flowchart of searching and selecting guidelines.

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Figure 2.

Bibliometric map of included studies.

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Table 1.

Baseline characteristics of RCTs and NRCTs.

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Figure 3.

Overall survival (OS) at 1-, 3- and 5-year in RCTs.

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Table 2.

Summary of finding table for HCC patients with tumor less than 5

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Table 3.

Summary of finding table for HCC patients with tumor size less than 5

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Figure 4.

Recurrence-free survival rate (RFS) at 1-, 3- and 5-year in RCTs.

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Figure 5.

Recurrence rate at 1-, 3- and 5-year in RCTs.

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Figure 6.

Complication rate of RCTs.

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Table 4.

Summary of finding table for Solitary HCC with tumor size≤3 cm and 3–5 cm in RCTs.

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Table 5.

Summary of finding table for HCC patients with tumor size between 3 and 5

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Table 6.

Summary of finding table for HCC patients with tumor size ≤3cm in NRCTs.

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Table 7.

Summary of finding table for solitary HCC patients with tumor size ≤2 cm in NRCTs.

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Table 8.

Publication bias of studies which were more than ten.

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