Table 1.
List of bioinformatics tools and databases used for sequence based function annotation.
Figure 1.
Computational framework used for annotating function of 429 HPs from H. influenzae.
Methodology is divided into three phases: PHASE I. H. influenzae HP characterization and sequence retrieval from online databases. PHASE II. The extensive analysis of sub-cellular localization, physicochemical parameters, virulence, function and domain present in HPs. PHASE III. This phase include assessment of predicted functions using the protein with known function from H. influenzae and reliable prediction of possible functions of HPs.
Figure 2.
Classification of 429 HPs into various groups by utilizing the functional annotation result of various bioinformatics tools.
The chart shows that there are 41% are enzymes, 20% proteins involve in transportation, 12% binding proteins, 7% bacteriophage related proteins and rest are proteins involved in cellular processes like transcription, translation, replication etc., among 429 HPs from H. influenzae.
Table 2.
List of annotated HPs from H. influenzae.
Table 3.
List of HPs with virulence factors in H. influenzae.