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Table 1.

MPS III Participant Information.

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Table 2.

Comparison of MPS III and Control Group Data on the Children’s Sleep Habits Rating Scale.

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Table 3.

Sleep Parameters (per night) for MPS III Participants Averaged over the Recording Period.

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Table 3 Expand

Figure 1.

Mean actigraphic results of MPS III (n = 8) and control groups (n = 8).

Error bars represent standard error of the mean. (A) Duration of time in bed. (B) Duration of night-time sleep. (C) Duration of daytime sleep. (D) Sleep onset latency. (E) Sleep efficiency. (F) Wake after sleep onset. * p<0.05, ** p<0.01.

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Table 4.

Comparison of Sleep Parameters in Children with MPS III and Controls.

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Figure 2.

Melatonin concentrations (average ± SEM) in MPS III patients and controls.

Saliva samples were collected at the times shown on. (A) First day of actigraphic monitoring. (B) Last day of actigraphic recording.

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Table 5.

Median (IQR) Melatonin Concentrations across Groups, Time points and Days.

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Table 5 Expand