Figure 1.
Significant differences in FA values between trauma-exposed victims with and without PTSD.
These clusters were shown in the WM of right anterior cingulate cortex, right middle temporal gyrus, right midbrain, and left gyrus rectus/medial orbitofrontal gyrus (2-sample t-test, P < 0.05, AlphaSim-corrected). Cold colors indicate decreases in FA. The left part of the figure represents the participant’s right side.
PTSD = posttraumatic stress disorder; FA = fractional anisotropy; WM = white matter.
Figure 2.
Significant differences in MD values between trauma-exposed victims with and without PTSD.
These clusters were shown in the WM of right superior frontal gyrus, and subcallosal gyrus (2-sample t-test, P < 0.05, AlphaSim-corrected). Cold colors indicate decreases in MD and warm colors indicate increases in MD. The left part of the figure represents the participant’s right side.
PTSD = posttraumatic stress disorder; MD = mean diffusivity; WM = white matter.
Figure 3.
The mean FA values in the left vmPFC in trauma-exposed victims diagnosed with PTSD within 1 or 6 months was negatively correlated with their CAPS scores at diagnosis
(P < 0.05 corrected for AlphaSim).
The right part of the figure represents the patient’s left side.
CAPS = clinician administered PTSD scale; PTSD = post-traumatic stress disorder; FA = fractional anisotropy; vmPFC = ventromedial prefrontal cortex.
Figure 4.
Significant differences in FA values between trauma-exposed victims with PTSD and healthy controls These clusters were shown in the WM of right inferior occipital gyrus, left superior temporal gyrus and left superior frontal gyrus, orbital part
(2-sample t-test, P < 0.05, AlphaSim-corrected).
Cold colors indicate decreases in FA. The left part of the figure represents the participant’s right side.
PTSD = posttraumatic stress disorder; FA = fractional anisotropy; WM = white matter.
Figure 5.
The follow-up scans of trauma-exposed victims with PTSD showed decreased FA in left insula WM compared with their baseline DTI scans
(paired t-sample t-test, P < 0.05, AlphaSim-corrected).
Cold colors indicate decreases in FA. The left part of the figure represents the participant’s right side.
PTSD = posttraumatic stress disorder; FA = fractional anisotropy.
Figure 6.
Scatter plot illustrating the relationship between the mean FA values in the insula in the follow-up scan of trauma-exposed victims with PTSD and the mean FA values in the vmPFC in their baseline DTI scans.
FA = fractional anisotropy; vmPFC = ventromedial prefrontal cortex.