Figure 1.
Flow of participants through each stage of the trial.
a WALK = walking to 65–75% of heart rate max, AIT = aerobic interval training to a 85–95% of heart rate max MVIT = Maximal volitional intensity training (‘all out’ exercise). b Participant unable to undertake exit VO2max because of injury unrelated to the study. c Four participants did not undertake exit VO2max: Exercise related injury n = 1, chest infection n = 2, participant exited early as dissatisfied with exercise program n = 1.
Figure 2.
Schematic representation of the three exercise prescriptions allocated 1:1∶1 at randomisation.
§ Number of repetitions in MVIT group increased over twelve weeks, as participant's fitness levels improved. WALK = walking, AIT = aerobic interval training, MVIT = maximal volitional intensity training.
Table 1.
Description of researchers' primary role in trial conduct and mechanisms for blinding.
Table 2.
Baseline characteristics for the entire cohort and the subgroup completing the exercise protocol.
Table 3.
Primary and secondary outcomes and other relevant parameters before and after the 12 week exercise program for the entire cohort.
Table 4.
Primary and secondary outcomes and other relevant parameters before and after the 12 week exercise program, by group.
Table 5.
Changes (post minus pre) in primary and secondary outcome measures and comparison between low intensity exercise and high intensity interval and maximal volitional intensity training.
Figure 3.
Changes in V02 max and time per week exercising, by treatment group.
Intention-to-treat analysis thus data on exercise time includes data from ‘non-adheres’, unable or unwilling to complete the exercise prescription. Data are means and standard errors estimated from the general linear model.
Table 6.
Attendance at exercise sessions and time spent exercising over 12 weeks, for all randomized participants (n = 49).