Figure 1.
Classification of laxative exposure for those who switched laxative type.
Figure 2.
The number of all laxative prescriptions and macrogol laxative prescriptions on the GPRD by calendar year and the growth of the GPRD population.
Table 1.
Patient characteristics for cases and controls on the index date.
Table 2.
Patient characteristics for cases and controls combined stratified by laxative exposure category and based on status on three years before the index date.
Figure 3.
Colorectal cancer risk associated with macrogol laxative exposure compared to non-macrogol only exposure for each of the backdated analysis sets.
Table 3.
Colorectal cancer risk associated with macrogol laxative exposure compared to non-macrogol only exposure for each of the backdated analysis sets.
Table 4.
Dose response association between macrogols, lactulose or other laxatives and colorectal cancer risk.