Table 1.
Demographic data, clinical characteristics, results of social cognitive testing and psychometric assessment obtained in patients with multiple sclerosis and group of healthy controls recruited for neuropsychological testing.
Table 2.
Results of Eyes test performance and MRI measures in patients with multiple sclerosis and group of healthy controls recruited for MRI examination.
Figure 1.
Assessment of total and regional T1 lesion volume in patients with multiple sclerosis.
A. T1 hypointense lesions are shown on a representative grayscale MPRAGE image (white arrows). B. Binary lesion map generated from outlined T1 hypointense lesions visualized in green. C. WM fiber tract atlas registered into native space of the MPRAGE image. D. Labeled lesion map derived from the binary lesion map after parcellation of the lesions with the use of the WM fiber tract atlas. The labeled lesion map was used to measure regional T1 white matter lesion volumes within each individual fiber bundle.
Figure 2.
Cortical areas of which thickness correlated with Eyes test performance in patients with multiple sclerosis.
Significance map from general linear model analysis of 49 patients with multiple sclerosis is displayed at each vertex of the inflated standardized brain. After correction for the effect of age, the Eyes test performance showed significant correlations (p<0.001) with cortical thickness of areas shown on the figure. P-values are presented in the color bar (logarithmic value).
Table 3.
Data of cortical thickness and area of brain regions showing correlation with the performance in the Faces test and Eyes test in patients with multiple sclerosis accounting for age.
Table 4.
Comparison of mean cortical thickness of brain areas showing correlation with Eyes test performance between patients with multiple sclerosis and healthy control group.