Figure 1.
Survival characteristics of the patients included in the database including histology of adenocarcinoma (adeno), squamous cell carcinoma (SCC) and large cell carcinoma (large), gender, stage (only with overall survival) and smoking history.
Table 1.
Clinical characteristics of the datasets included in the analysis.
Figure 2.
Validation of 29 previously published NSCLC biomarkers.
Meta-analysis of these genes and signatures in the respective sample cohort yielded CCNE1, CDC2 and CADM1 as the best performing individual genes (A–C) and the signature of Yamauchi et al. (D). A funnel plot depicting the hazard ratios (with confidence intervals) versus sample number for CDC2 and VEGF shows more reliable estimation with larger database sizes (E–F).
Table 2.
Performance of previously published biomarker candidates associated with survival in non-small-cell lung cancer.