Table 1.
Comparison of the main demographic parameters between the three groups of subjects.
Table 2.
Comparison of the main neuropsychological variables between the three groups of subjects.
Figure 1.
Results of the voxel-based morphometric (VBM) analysis: comparison of grey matter volume between the groups of subjects.
A- Zones of decreased grey matter volume in bvFTD patients compared to controls (p<0.05 after FWE correction for multiple comparisons). B- Zones of decreased grey matter volume in PSP patients compared to controls (p<0.05 after FWE correction for multiple comparisons). C- Zones of decreased grey matter volume in bvFTD patients compared to PSP patients (k = 100 voxels, p<0.001). Abbreviations: R: right, L: left, A: anterior, P: posterior, bvFTD: behavioral variant of frontotemporal dementia, PSP: progressive supranuclear palsy.
Table 3.
Detailed results of the comparative analysis of grey matter volume.
Figure 2.
Results of the voxel-based morphometric (VBM) analysis: comparison of white matter volume between the groups of subjects.
A- Zones of decreased white matter volume in bvFTD patients compared to controls (p<0.05 after FWE correction for multiple comparisons). B- Zones of decreased white matter volume in PSP patients compared to controls (p<0.05 after FWE correction for multiple comparisons). C- Zones of decreased white matter volume in PSP patients compared to bvFTD patients (p<0.05 after FWE correction for multiple comparisons). Abbreviations: R: right, L: left, A: anterior, P: posterior, bvFTD: behavioral variant of frontotemporal dementia, PSP: progressive supranuclear palsy.
Table 4.
Detailed results of the comparative analysis of white matter volume.
Figure 3.
Results of the voxel-based morphometric (VBM) analysis: correlations between grey matter volume and neuropsychological variables in bvFTD patients.
A- Positive correlation between grey matter volume and the interference T-score in the Stroop test (k = 100 voxels, p<0.001). B- Positive correlation between grey matter volume and the number of categories found in the WCST (k = 100 voxels, p<0.001). C- Positive correlation between grey matter volume and letter fluency (k = 100 voxels, p<0.001). D- Positive correlation between grey matter volume and the MDRS initiation score (k = 100 voxels, p<0.001). E- Positive correlation between grey matter volume and the MDRS attention score (k = 100 voxels, p<0.001). F- Positive correlation between grey matter volume and the concept score (k = 100 voxels, p<0.001). Abbreviations: R: right, L: left, A: anterior, P: posterior, WCST: Wisconsin Card Sorting Test, MDRS: Mattis Dementia Rating Scale.
Table 5.
Detailed results of the correlation analysis of grey matter volume in bvFTD patients.
Figure 4.
Results of the voxel-based morphometric (VBM) analysis: correlations between white matter volume and neuropsychological variables in bvFTD patients.
A- Positive correlation between white matter volume and the interference T-score in the Stroop test (k = 100 voxels, p<0.001). B- Positive correlation between white matter volume and the number of categories found in the WCST (k = 100 voxels, p<0.001). C- Positive correlation between white matter volume and the MDRS attention score (k = 100 voxels, p<0.001). Abbreviations: R: right, L: left, A: anterior, P: posterior, WCST: Wisconsin Card Sorting Test, MDRS: Mattis Dementia Rating Scale.
Table 6.
Detailed results of the correlation analysis of white matter volume in bvFTD patients.