Figure 1.
Navigation guides the approach and 5-ALA fluorescence identifies tumor remnant during re-do surgery.
(A) Intraoperative neuronavigation guides the surgical approach towards the contrast enhancing tumor remnant (green crosslines = pointer navigation). (B) White light inspection of the surgical cavity. (C) 5-ALA induced fluorescence reveals tumor remnant under blue light (arrow).
Figure 2.
Histological analysis of tumor remnant resected during re-do surgery in Patient #8.
(A) Areas of viable tumor (center) as well as radiation-type necrosis. (B) At higher magnification, pleomorphic astrocytic tumor cells – some of them with bizarre nuclear atypia – are seen. Scale bar corresponds to 400 micrometer (A) and 50 micrometer (B).