Figure 1.
Glutathione of in vitro stored lenses.
In vitro Optisol-GS stored lenses showed a rapid drop in concentration at 1½ hour, which was not observed with castor oil. A significant effect of the storage media is observed after 72 hours, with castor oil stored lenses retaining three times the amount of Optisol-GS stored lenses. Total glutathione is shown as full lines, GSH as large dotted and GSSG as small dotted lines. Bold lines show the progression in Optisol-GS and thin lines in castor oil.
Figure 2.
Glutathione in post mortem stored lenses.
Storage inside the eye retain glutathione in the lens, although affected by a redox shift of decreased GSH and increased GSSG concentrations. GSSG quickly drop to similar levels as in vitro stored lenses, whereas GSH is lost at a slower rate without any rapid drops. Total glutathione is shown as full lines, GSH as large dotted and GSSG as small dotted lines. Bold lines show the progression in Optisol-GS and thin lines in castor oil.