Figure 1.
Gene expression profiles of quiescent pediatric IBD patients.
Global gene expression profiles of peripheral blood leukocytes were analysed using principal components analysis (PCA). Samples with higher similarity between gene expression profiles cluster more strongly together in the PCA space. Crohn’s disease (red) and ulcerative colitis (green) patients with quiescent disease are not different from each other and form a heterogeneous cluster that is distinct from controls (blue).
Figure 2.
Correlation plot of quiescent IBD patients involving 2957 probe sets.
Pair-wise correlations between the samples are depicted in a Pearson’s correlation plot. The colours of the cells relate to Pearson’s correlation coefficient values, with deeper colours indicating higher positive (red) or negative (blue) correlations. This Pearson’s correlation plot revealed three distinct groups (A, B, C). Controls are annotated to group A.
Table 1.
Group characteristics.
Table 2.
Top canonical pathways Group A/B/C vs Control.
Table 3.
Top canonical pathways Group A/B/C vs Group and Controls.