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Table 1.

List of 15 cancer cell types and their corresponding normal cell types.

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Figure 1.

Directed enzyme-centric metabolic networks of cancer and normal breast cells.

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Table 2.

A summary of the different networks, software and parameters used for each topological analysis.

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Figure 2.

Corresponding Motif IDs of size 3 used in this study.

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Table 3.

Primary topological measures related to directed metabolite-centric networks.

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Figure 3.

Cluster distribution in enzyme and metabolite-centric cancer and normal networks.

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Table 4.

Motif finding in directed metabolic and enzyme-centric breast networks.

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Figure 4.

Distribution of drug targets in twelve different centralities.

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Figure 5.

First 17 clusters of liver enzyme-centric cancer network.

Drug targets (green nodes) are in cluster number 14.

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