Figure 1.
Regional homogeneity (ReHo) results within the migraine patients without aura (MWoA) and healthy controls.
(a) MwoA ReHo map, (b) healthy controls ReHo map (p <0.05, FWE corrected).
Figure 2.
Abnormal regional homogeneity (ReHo) changes between groups.
Compared with healthy controls, decreased ReHo in the insula, the rostral anterior cingulate cortex (rACC), the supplementary motor area (SMA) and the cuneus were shown similarly in the whole migraine patients without aura (MWoA) group (Figure 2.a), SDS (+) group (Figure 2.b) and SDS (−) group (Figure 2.c) (p < 0.05, FWE corrected), which was indicate by a cool color. It is noteworthy that the caudate showed increased ReHo in the SDS (−) group compared with healthy controls (at the bottom of Figure 2.c shown in a warm color), and compared with the SDS (+) group (at the bottom of Figure 2.d in a cool color) (p < 0.05, FWE corrected). As indicated by the straight lines with the arrow, the average ReHo values of the caudate in Figure 2.c was significantly positively correlated with duration of migraine in the SDS (−) group separately. (SDS (+) group: migraine patients without aura with high depressive symptoms, self-rating depression scale (SDS) scores > 49; SDS (−) group: migraine patients without aura with low depressive symptoms, SDS scores ≤ 49.)