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Figure 1.

Flowchart of study subjects.

CAS, coronary artery spasm.

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Table 1.

Baseline characteristics.

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Table 2.

Gender-specific baseline characteristics between study groups.

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Table 3.

Gender-specific univariate and multivariate analysis of variables associated with CAS.

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Table 4.

Gender-specific stratified analysis for CAS of hs-CRP tertiles, and diabetes mellitus or hypertension.

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Figure 2.

Multivariate-adjusted association of DM and HTN with risk of CAS according to different models.

The odds ratios in the overall study population, women and men are represented by diamonds, circles and squares, respectively. The horizontal lines represent the 95% confidence intervals (CI). Adjusted logistic regression variables include age, body mass index, smoking, left ventricular ejection fraction, cholesterol, hemoglobin, hematocrit, platelet and hs-CRP tertiles other than the stratified variable per se. CAS, coronary artery spasm; DM, diabetes mellitus; hs-CRP, high-sensitivity C-reactive protein; HTN, hypertension.

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Table 5.

Univariate and multivariate Cox regression analysis for major adverse cardiovascular events and coronary events.

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Figure 3.

Outcome in patients with CAS in relation to hs-CRP tertiles.

(A) Kaplan-Meier survival curves for major adverse cardiovascular event-free survival showing the frequency was lowest in patients with the highest hs-CRP tertile (p = 0.010) (log-rank test). (B) Coronary events showing significantly more events in patients with the highest hs-CRP tertile (p = 0.021) (log-rank test). CAS, coronary artery spasm; hs-CRP, high-sensitivity C-reactive protein.

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Figure 3 Expand