Table 1.
Spray dryer settings used for model fitting and validation.
Table 2.
Spray dryer settings used for relative humidity measurements.
Figure 1.
Schematic representation of a spray dryer (left) and the simplified spray dryer model (right).
Output variables include but are not restricted to the outlet temperature (Tout).
Figure 2.
Overview of iteration steps in our spray dryer model.
Details are left out for clarity. Model expansion for relative humidity at the spray dryer outlet (RHout) will be discussed in the results.
Figure 3.
Modeled (grey) and experimental (black) outlet temperature used to determine dair.
Aspirator flow was set at either 12 m3n/hr (circle) or 22 m3n/hr (triangle), while the liquid feed flow was kept constant at 0 mL/min. Thickness of the lines indicate the 95% confidence interval of the modeled outlet temperature.
Figure 4.
Modeled (grey) and experimental (black) outlet temperature.
Inlet temperature was set at 100°C (circle), 150°C (triangle), or 200°C (square). Aspirator flow was kept constant at 22 m3n/hr. Thickness of the lines indicate the 95% confidence interval of the modeled outlet temperature.
Figure 5.
Modeled (grey) and experimental (black) relative humidity.
Measurements were done at an inlet temperature of 90°C (circle), 70°C (triangle), or 50°C (square). Results shown at the top (A) were obtained with an aspirator flow of 12 m3n/hr and the results on the bottom (B) with 22 m3n/hr. Thickness of the lines indicate the 95% confidence interval of the modeled relative humidity (3.1% RH).
Table 3.
Trehalose and inulin yield depending on spray drying conditions.a