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Figure 1.

A flow chart depicting imaging acquisition, generation of geometrical model, FE simulation and hemodynamic analysis.

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Figure 2.

End-to-side SVG obtained from patient CTA, where θ is the graft angle between SVG and coronary artery.

A blunt velocity profile was used in the FE simulation.

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Figure 3.

The anastomosis between SVG and coronary artery obtained from patient CTA with: (a) small anastomotic stenosis (area stenosis<20%) and the distribution of (b) time-averaged (over a cardiac cycle) WSS (Unit: Dynes⋅cm−2), (c) OSI and (d) time-averaged flow velocity (Unit: cm/s); (e) mild anastomotic stenosis (40%<area stenosis<60%) and the distribution of (f) time-averaged WSS (Unit: Dynes⋅cm−2), (g) OSI and (h) time-averaged flow velocity (Unit: cm/s).

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Figure 4.

The distribution of time-averaged (over a cardiac cycle) WSS (Unit: Dynes⋅cm−2) at the anastomosis between SVG and coronary artery for geometrical models as: (a) and θ = 45° (an idealized case, where equal to the CSA of proximal artery in Fig. 3e); (b) and θ = 45° (a simulated decrease of graft CSA); (c) and θ = 85° (a simulated increase of graft angle); and (d) and θ = 85° (a simulated decrease of graft CSA as well as a simulated increase of graft angle).

Region A refers to the toe region in coronary artery while Region B is the toe region in venous graft. Region C refers to the heel region. Region D represents coronary artery wall opposite to junction orifice.

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Figure 4 Expand

Figure 5.

The distribution of OSI at the anastomosis between SVG and coronary artery in correspondence with Fig. 4.

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Figure 5 Expand

Figure 6.

The distribution of time-averaged (over a cardiac cycle) flow velocity (Unit: cm/s) at the anastomosis between SVG and coronary artery in correspondence with Fig. 4.

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Figure 6 Expand

Figure 7.

Mean ± SD (a) WSS and (b) OSI in Region A (averaged over all nodes in the region).

Region A has surface area of 2.4, 6.8, 7.2, and 7.32 for and θ = 45°; and θ = 45°; and θ = 85°; and and θ = 85°, respectively.

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Figure 8.

(a) Mean ± SD WSSG (Unit: Dynes⋅cm−3) in Region B (averaged over all nodes in the region), (b) Mean ± SD WSSG in Region D (averaged over all nodes in the region).

Region B has surface area of 1.2, 2.8, 3.1, and 2.4 mm2 for and θ = 45°; and θ = 45°; and θ = 85°; and and θ = 85°, respectively. Region D has surface area of 2.4, 3.3, 4.2, and 4.3 mm2, accordingly.

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Figure 8 Expand