Figure 1.
Plasma MIC-1, PAPP-A and hCG concentrations.
(A) Mean MIC-1 levels across gestation. (B) Box and Whisker plots of MoM MIC1 levels in the ongoing pregnancy (n=428) and miscarriage cohorts (n=34) (C) Mean PAPP-A levels across gestation (D) Box and Whisker plots MoM PAPP-A levels in the ongoing pregnancy (n=312) and miscarriage cohort (n=11) (E) Mean hCG levels across gestation (F) Box and Whisker plots of MoM hCG levels in the ongoing pregnancy (n=428) and miscarriage (n=34) cohorts. *P=0.036, **P=0.0025, *** P=0.0008. For Figure 1A,C,E, the numbers for each gestation were: 5 weeks n=19; 6 weeks n=132; 7 weeks n=95; 8 weeks n=65; 9 weeks n=54; 10 weeks n=35; 11 weeks n=21; 12 weeks n=6. For Figure 1A,C,E error bars are standard error of the mean.