Figure 1.
Kaplan-Meier analysis of local control rate stratified according to the median value of Ktrans.
Figure 2.
Local control in a 52-year-old man with hypopharyngeal SCC after chemoradiation.
A. A pretreatment axial-enhanced MRI shows the right hypopharynx tumor (arrow). B. The corresponding PWI map shows the tumor with a Ktrans value of 0.614 min-1. C. The corresponding ADC map shows the tumor with an ADC value of 0.98 × 10-3 mm2/s. D. Post-treatment axial-enhanced MRI shows the regression of the right hypopharynx tumor. A 18-month clinical and imaging follow-up did not disclose any tumor growth.
Figure 3.
Local failure in a 61-year-old man with oropharyngeal SCC after chemoradiation.
A. A pretreatment axial-enhanced MRI shows the oropharynx tumor (arrow). B. The corresponding PWI map shows the tumor with a Ktrans value of 0.336 min-1. C. The corresponding ADC map shows the tumor with an ADC value of 0.76 × 10-3 mm2/s. D. Post-treatment axial-enhanced MRI shows a residual left oropharynx tumor (arrow) which was proven by endoscopic biopsy.
Figure 4.
Scatterplots of Ktrans in the local control (LC, n= 41) and local failure (LR, n=17) groups.
Figure 5.
Scatterplots of SUVmax in the local control (LC, n= 41) and local failure (LR, n=17) groups.
Figure 6.
Scatterplots of the incidence of local failure with respect to the relationship between Ktrans and SUVmax.
The entire area of interest was divided into subsections (lines) using a cut-off of 0.45 min-1 for Ktrans and a cut-off of 13.76 g/mL for SUV max.
Figure 7.
Subgroup analysis of local control rates according to different combinations of Ktrans (cut-off = 0.45 min-1) and SUVmax (cut-off = 13.76 g/mL).