Figure 1.
Flow chart showing patients excluded from analysis.
Of the 20 excluded patients, 17 were initiated on TDF-based first-line therapy, dual NRTI therapy or were already receiving a second-line regimen at time of genotype. The three protocol violations were: two patients on treatment for less than a year, and one with viral load <1000 copies/ml at the time of genotyping.
Table 1.
Demographic and clinical characteristics.
Figure 2.
NNRTI mutations.
Figure 3.
NRTI mutations, including summary of proportion with thymidine analogue mutations (TAMs).
Table 2.
Univariate analysis of factors associated with compromised standard second-line regimen (genotypic susceptibility score <2).
Table 3.
Summary of acquired drug resistance studies in adults treated with first-line antiretroviral therapy in South Africa.