Figure 1.
Representative patterns of line probe assay (GenoType MTBDR-plus) strip.
Lane 1, susceptible to rifampicin (RIF) and isoniazid (INH); Lane 2, MDR- TB (rpoB S531L mutation andinhA C15T mutation); Lane 3, rifampicin monoresistant (mutation at rpoB530–533 gene region); Lane 4, absence of TUB band; Lan 5, isoniazid monoresistant (katG S315T1 mutation); Lane 6, DNA positive control (sensitive to rifampicin and isoniazid); Lane 7, DNA negative control.
Table 1.
M. tuberculosis detection by LPA vs. solid culture in 269 smear positive sputum samples.
Table 2.
Performance of LPA test as compared to LJ DST in detecting resistance to rifampicin, isoniazid, and MDR-PTB in 242 smear positive sputum samples.
Table 3.
Band patterns of drug resistant Mycobacterium tuberculosis strains using line probe assay.