Table 1.
Clinical data.
Figure 1.
NDGs were isolated from the blood of HIV+ patients with CD4+ T cell counts >350 (n = 11) or <350 cells/µL (n = 10) as described in materials and methods and the expression levels of phenotypic markers were determined by flow cytometry. Isotype controls: <1%. Statistical significance was determined by a two-tailed Mann-Whitney test. Box = interquartile range and median; whiskers = range.
Table 2.
Phenotype of NDGs.
Figure 2.
Correlation between CD4+ T cells and phenotypic markers.
NDGs were isolated from the blood of HIV+ patients (n = 21) as described in materials and methods and the expression levels of phenotypic markers were determined by flow cytometry. Correlation between CD4+ T cell counts and phenotypic markers was determined by a Spearman's rank test.
Table 3.
NDGs: Correlation between CD4+ T cell counts and MFIs.
Figure 3.
Correlation between viral load and phenotypic markers.
NDGs were isolated from the blood of HIV+ patients (n = 21) as described in materials and methods and the expression levels of phenotypic markers were determined by flow cytometry. Correlation between viral load and phenotypic markers was determined by a Spearman's rank test.
Table 4.
NDGs: Correlation between viral loads and MFIs.
Table 5.
Phenotype of LDGs.
Table 6.
LDGs: Correlation between CD4+ T cell counts and MFIs.
Table 7.
Correlation between viral loads and MFIs.
Figure 4.
Phenotypes of NDGs and LDGs in CD4low and CD4high HIV+ patients.
PBMCs and NDGs were isolated from the blood of HIV+ patients with CD4+ T cell counts >350 (n = 11) or <350 cells/µL (n = 10) as described in materials and methods and the expression levels of phenotypic markers were determined by flow cytometry. Isotype controls: <1%. Statistical significance was determined by a two-tailed Mann-Whitney test. Box = interquartile range and median; whiskers = range.
Table 8.
LDGs and NDGs in HIV+ patients in CD4low HIV+ patients.
Table 9.
LDGs and NDGs in HIV+ patients in CD4high HIV+ patients.