Figure 1.
Typical flow cytometric data for lymphocyte, CD4+ memory, and CD4+ naive cell populations.
At least 30,000 lymphocytes were evaluated and were gated based on their forward (FCS; X-axis) and side (SCS; Y-axis) scatter (Panels A&B). Memory and naive cell subpopulations were gated by positive surface staining for CD4 (Y-axis, panels C–F); memory cells were gated by positive surface staining for CD45RO (X-axis, panels C&D); naive cells were gated by positive surface staining for CD45RA (X-axis, panels E&F). Typical data from respective isotype controls (Panels A, C, and E) and fluorescently labeled samples (Panels B, D, and F) are shown.
Table 1.
Characteristics of the MESA sample population being studied.
Table 2.
Pearson correlation coefficients for CD4+ naive and memory cell subpopulations with biomarkers of inflammation, CVD risk, and infection.
Table 3.
Regression models for CD4+ naive and memory cell subpopulations.
Table 4.
Final regression model for coronary artery calcification.
Table 5.
Final regression models for common carotid intimal media thickness in European-Americans.